Site-selected incorporation of 5-carboxymethylaminomethyl(- 2-thio)uridine into RNA sequences by phosphoramidite chemistry
| dc.contributor.author | Leszczyńska, Grażyna | |
| dc.contributor.author | Pięta, Jakub | |
| dc.contributor.author | Woźniak, Karolina | |
| dc.contributor.author | Małkiewicz, Andrzej | |
| dc.date.accessioned | 2016-02-08T07:53:42Z | |
| dc.date.available | 2016-02-08T07:53:42Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | 5-Carboxymethylaminomethyluridine (cmnm5U) and 5-carboxymethylaminomethyl-2-thiouridine (cmnm5s2U) are located at the wobble position in several cytosolic and mitochondrial tRNA sequences. In this paper, we report the first site-selected incorporation of cmnm5U and cmnm5s2U into RNA sequences by phosphoramidite chemistry on a CPG solid support. Trifluoroacetyl and 2-(trimethylsilyl)ethyl were selected for the protection of the amine and carboxyl functions, respectively. | en_EN |
| dc.identifier.citation | Organic & Biomolecular Chemistry, Vol. 12, Issue 7, pages 1052-1056 | |
| dc.identifier.uri | http://hdl.handle.net/11652/1126 | |
| dc.identifier.uri | http://pubs.rsc.org/en/content/articlelanding/2014/ob/c3ob42302f#!divAbstract | |
| dc.language.iso | en | en_EN |
| dc.relation.ispartofseries | Organic & Biomolecular Chemistry, Vol. 12, Issue 7, 2014 | en_EN |
| dc.title | Site-selected incorporation of 5-carboxymethylaminomethyl(- 2-thio)uridine into RNA sequences by phosphoramidite chemistry | en_EN |
| dc.type | Artykuł | pl_PL |
| dc.type | Article | en_EN |