Artykuły (WCh)

Stały URI dla kolekcjihttp://hdl.handle.net/11652/155

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  • Pozycja
    Profesor Ryszard Bodalski – wspomnienia
    (Wydział Chemiczny, Politechnika Łódzka, 2019) Janecki, Tomasz; Albrecht, Łukasz
  • Pozycja
    Profesor Henryk Krawczyk – wspomnienia
    (Wydział Chemiczny, Politechnika Łódzka, 2018) Albrecht, Łukasz
  • Pozycja
    Organocatalytic Enantioselective Approach to Spirocyclic Δβ,γ-Butenolides
    (2014) Hejmanowska, Joanna; Dzięgielewski, Marek; Kowalczyk, Dorota; Albrecht, Łukasz
    A novel method for the preparation of the spirocyclic Δβ,γ-butenolides is presented. The developed strategy is based on a trienamine-mediated [4+2]-cycloaddition between (E)-3-alkylidene- 5-arylfuran-2(3H)-ones and 2,4-dienals. Target products containing three contiguous centres including one quaternary are efficiently formed in a highly enantiomerically enriched form in the presence of the silyl-protected diphenylprolinol aminocatalyst.
  • Pozycja
    A Convenient Approach to a Novel Group of Quaternary Amino Acids Containing­ a Geminal Bisphosphonate Moiety
    (2014) Dzięgielewski, Marek; Hejmanowska, Joanna; Albrecht, Łukasz
    Quaternary amino acids containing a geminal bisphosphonate moiety have been synthesized for the first time. The developed two-step reaction sequence utilizes the Michael addition of α-substituted azlactones to a vinylidene bisphosphonate as the key step. The reaction proceeds under catalytic conditions with excellent regioselectivity. Subsequent, acid-mediated azlactone ring opening affords the target quaternary amino acids with good overall yields. Attempts to develop an enantioselective version of the synthetic strategy are described.