Ibuprofen-tyrosine (Val-Tyr, Val-Tyr-Val) interactions. Theoretical and experimental studies

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dc.contributor.authorKowalska-Baron, Agnieszka
dc.contributor.authorBrychtowa, Michaela
dc.contributor.authorPetrović, Ivana
dc.contributor.authorPassos, Sene Igor
dc.contributor.authorQuinones, Paloma
dc.contributor.authorSogorkova, Jana
dc.date.accessioned2015-06-03T11:11:22Z
dc.date.available2015-06-03T11:11:22Z
dc.date.issued2011
dc.description.abstractIn this work, the interactions between ibuprofen and tyrosine as well selected tyrosine-containing oligopeptides (Val-Tyr, Val-Tyr-Val) have been studied using both experimental (absorption and fluorescence spectroscopy) and theoretical (the PM3 method) techniques. The experimentally obtained values of association constant together with free Gibbs energy of association for the studied tyrosine-ibuprofen and Val- Tyr-; Val-Tyr-Val-ibuprofen complexes have been determined. The obtained results indicated that the mechanism of action of ibuprofen is most probably based on the hydrogen bonding interaction which involves hydroxyl group of tyrosine.en_EN
dc.formatapplication/pdf
dc.identifier.citationBiotechnology and Food Science, 2011 Vol.75 nr 2 s.15-26
dc.identifier.issn2084-0136
dc.identifier.other0000035888
dc.identifier.otherKontynuacja Zeszytów Naukowych Politechniki Łódzkiej, serii Chemia Spożywcza i Biotechnologia.
dc.identifier.urihttp://hdl.handle.net/11652/275
dc.language.isoenen_EN
dc.publisherWydawnictwo Politechniki Łódzkiejpl_PL
dc.publisherLodz University of Technology. Pressen_EN
dc.relation.ispartofseriesZeszyty Naukowe Politechniki Łódzkiejpl_PL
dc.relation.ispartofseriesBiotechnology and Food Scienceen_EN
dc.titleIbuprofen-tyrosine (Val-Tyr, Val-Tyr-Val) interactions. Theoretical and experimental studiesen_EN
dc.typeArticleen_EN
dc.typeArtykułpl_PL

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