Conditions Regulating Tumor Cell Behaviour in Biological Systems with Memory of States

Abstract

For biological systems with memory of states there were found conditions which regulate tumor cell behaviour. These conditions depend on parameters of the multi-parametric space. Based on the Masing–Bouc-Wen’s framework, the state memory in the biological system was simulated by means of supplemental state variables (internal variables). The additional state variables were introduced into the generalized non-linear multi-scale diffusion cancer invasion model and the chaotic cancer attractors were found. To quantify chaotic cancer attractors, the technique based on the wandering trajectories analysis was applied.