Organocatalytic Enantioselective Approach to Spirocyclic Δβ,γ-Butenolides
Oglądaj/ Otwórz
Data wydania
2014Autor
Hejmanowska, Joanna
Dzięgielewski, Marek
Kowalczyk, Dorota
Albrecht, Łukasz
Metadane
Pokaż pełny rekordAbstrakt
A novel method for the preparation of the spirocyclic Δβ,γ-butenolides is presented. The developed strategy is based on a trienamine-mediated [4+2]-cycloaddition between (E)-3-alkylidene- 5-arylfuran-2(3H)-ones and 2,4-dienals. Target products containing three contiguous centres including one quaternary are efficiently formed in a highly enantiomerically enriched form in the presence of the silyl-protected diphenylprolinol aminocatalyst.
URI
http://hdl.handle.net/11652/1107https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0034-1378905
Zbiory
- Artykuły (WCh) [128]