Organocatalytic Enantioselective Approach to Spirocyclic Δβ,γ-Butenolides
| dc.contributor.author | Hejmanowska, Joanna | |
| dc.contributor.author | Dzięgielewski, Marek | |
| dc.contributor.author | Kowalczyk, Dorota | |
| dc.contributor.author | Albrecht, Łukasz | |
| dc.date.accessioned | 2016-02-05T08:23:13Z | |
| dc.date.available | 2016-02-05T08:23:13Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | A novel method for the preparation of the spirocyclic Δβ,γ-butenolides is presented. The developed strategy is based on a trienamine-mediated [4+2]-cycloaddition between (E)-3-alkylidene- 5-arylfuran-2(3H)-ones and 2,4-dienals. Target products containing three contiguous centres including one quaternary are efficiently formed in a highly enantiomerically enriched form in the presence of the silyl-protected diphenylprolinol aminocatalyst. | en_EN |
| dc.identifier.citation | Synlett, Vol. 25(20), pages 2957-2961 | |
| dc.identifier.uri | http://hdl.handle.net/11652/1107 | |
| dc.identifier.uri | https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0034-1378905 | |
| dc.language.iso | en | en_EN |
| dc.relation.ispartofseries | Synlett, Vol. 25(20), 2014 | en_EN |
| dc.subject | asymmetric synthesis | en_EN |
| dc.subject | aminocatalysis | en_EN |
| dc.subject | trienamines | en_EN |
| dc.subject | Δβ,γ-butenolides | en_EN |
| dc.subject | quaternary stereogenic center | en_EN |
| dc.title | Organocatalytic Enantioselective Approach to Spirocyclic Δβ,γ-Butenolides | en_EN |
| dc.type | Artykuł | pl_PL |
| dc.type | Article | en_EN |