Fabrication of Plga/Hap and Plga/Phb/Hap Fibrous Nanocomposite Materials for Osseous Tissue Regeneration
Ładowanie...
Data
2014
Tytuł czasopisma
ISSN czasopisma
Tytuł tomu
Wydawca
Wydawnictwo Politechniki Łódzkiej. Wydział Technologii Materiałowych i Wzornictwa Tekstyliów
Lodz University of Technology. Press - Faculty of Material Technologies and Textile Design
Lodz University of Technology. Press - Faculty of Material Technologies and Textile Design
Abstrakt
The study presents the manufacturing of nanofibrous structures as osteoconductive, osteoinductive materials for osseous tissue regeneration. The fibrous structures were obtained by electrospinning of poly(l-lactide-coglicolide) (PLGA) with addition of hydroxyapatite (HAp) and of a blend of PLGA with polyhydroxybutyrate with HAp
added. The polymers used in the experiment were synthesised by an innovative method with a zirconium catalyst. First, the optimal electrospinning process parameters were selected. For the characterisation of the obtained osseous tissue reconstruction materials, the physical, macroscopic, functional, mechanical and thermal properties
as well as crystallinity index were studied. The study of the radiation sterilisation influence on average molar mass, thermal and mechanical properties was made in order to analyse the degradation effect.
Opis
Słowa kluczowe
electrospinning, resorbable material, implant, osseous tissue regeneration, hydroxyapatite
Cytowanie
Autex Research Journal, Vol. 14, Issue 2, Pages 95–110