Leonurus cardiaca L. herb - a derived extract and an ursolic acid as the factors affecting the adhesion capacity of Staphylococcus aureus in the context of infective endocarditis

Uproszczony widok
dc.contributor.authorMicota, Bartłomiej
dc.contributor.authorSadowska, Beata
dc.contributor.authorPodsędek, Anna
dc.contributor.authorRedzynia, Małgorzata
dc.contributor.authorRóżalska, Barbara
dc.date.accessioned2016-02-04T07:43:46Z
dc.date.available2016-02-04T07:43:46Z
dc.date.issued2014
dc.description.abstractThe objective was an assessment of the impact of Leonurus cardiaca L. extract (LCE) and ursolic acid (UA) on the adhesive properties of Staphylococus aureus NCTC 8325 strain, expressing virulence factors important in the pathogenesis of infective endocarditis. The adhesion and biofilm formation of bacteria cultured in the presence of subinhibitory concentrations of LCE or UA on the abiotic surface or covered with fibrinogen, fibronectin or collagen, were evaluated. Inhibitory effects of LCE and UA on staphylococcal adherence to both types of surface were demonstrated. This, in the case of UA, resulted in a significant reduction of biofilm formation.en_EN
dc.formatapplication/pdf
dc.identifier.citationActa Biochimica Polonica, Vol. 61, Issue 2, pages 385-388
dc.identifier.other0000045325
dc.identifier.urihttp://hdl.handle.net/11652/1084
dc.identifier.urihttp://www.actabp.pl/#File?./html/2_2014/385.html
dc.language.isoenen_EN
dc.publisherPolish Biochemical Societyen_EN
dc.publisherCommittee of Biochemistry and Biophysics Polish Academy of Sciencesen_EN
dc.relation.ispartofseriesActa Biochimica Polonica, Vol. 61, Issue 2, 2014en_EN
dc.subjectECMen_EN
dc.subjectLeonurus cardiacaen_EN
dc.subjectursolic aciden_EN
dc.subjectStaphylococcus aureusen_EN
dc.titleLeonurus cardiaca L. herb - a derived extract and an ursolic acid as the factors affecting the adhesion capacity of Staphylococcus aureus in the context of infective endocarditisen_EN
dc.typeArticleen_EN
dc.typeArtykułpl_PL

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