Hejmanowska, JoannaDzięgielewski, MarekKowalczyk, DorotaAlbrecht, Łukasz2016-02-052016-02-052014Synlett, Vol. 25(20), pages 2957-2961http://hdl.handle.net/11652/1107https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0034-1378905A novel method for the preparation of the spirocyclic Δβ,γ-butenolides is presented. The developed strategy is based on a trienamine-mediated [4+2]-cycloaddition between (E)-3-alkylidene- 5-arylfuran-2(3H)-ones and 2,4-dienals. Target products containing three contiguous centres including one quaternary are efficiently formed in a highly enantiomerically enriched form in the presence of the silyl-protected diphenylprolinol aminocatalyst.enasymmetric synthesisaminocatalysistrienaminesΔβ,γ-butenolidesquaternary stereogenic centerArtykuł