A Tandem Conjugate Addition–Intramolecular Horner–Wadsworth–Emmons Olefination Approach to the Synthesis of Cyclopentene[c]chroman-2-ones and Cyclopent-1-enecarboxylates

Abstrakt

A strategically new approach to cyclopentene[c]chroman- 2-ones and cyclopent-1-enecarboxylates by tandem Michael– Horner–Wadsworth–Emmons reaction of 2,5-hexanedione with 3-(diethoxyphosphoryl)coumarins is described. The products were obtained as single diastereoisomers in high yields.

Opis

Słowa kluczowe

Michael addition, Horner–Wadsworth–Emmons olefination, tandem reaction, annulations, 1,5,7-triazabicyclo[4.4.0]dec- 5-ene

Cytowanie

Synlett, Vol. 25 no.2, s. 280-282