Fabrication of Plga/Hap and Plga/Phb/Hap Fibrous Nanocomposite Materials for Osseous Tissue Regeneration

dc.contributor.authorKrucińska, Izabella
dc.contributor.authorChrzanowska, Olga
dc.contributor.authorBoguń, Maciej
dc.contributor.authorKowalczuk, Marek M.
dc.contributor.authorDobrzyński, Piotr
dc.date.accessioned2016-02-03T09:26:39Z
dc.date.available2016-02-03T09:26:39Z
dc.date.issued2014
dc.description.abstractThe study presents the manufacturing of nanofibrous structures as osteoconductive, osteoinductive materials for osseous tissue regeneration. The fibrous structures were obtained by electrospinning of poly(l-lactide-coglicolide) (PLGA) with addition of hydroxyapatite (HAp) and of a blend of PLGA with polyhydroxybutyrate with HAp added. The polymers used in the experiment were synthesised by an innovative method with a zirconium catalyst. First, the optimal electrospinning process parameters were selected. For the characterisation of the obtained osseous tissue reconstruction materials, the physical, macroscopic, functional, mechanical and thermal properties as well as crystallinity index were studied. The study of the radiation sterilisation influence on average molar mass, thermal and mechanical properties was made in order to analyse the degradation effect.en_EN
dc.formatapplication/pdf
dc.identifier.citationAutex Research Journal, Vol. 14, Issue 2, Pages 95–110
dc.identifier.issn1470-9589
dc.identifier.otherISSN (Online) 2300-0929
dc.identifier.urihttp://hdl.handle.net/11652/1065
dc.identifier.urihttp://www.degruyter.com/view/j/aut.2014.14.issue-2/aut-2014-0006/aut-2014-0006.xml?format=INT
dc.language.isoenen_EN
dc.publisherWydawnictwo Politechniki Łódzkiej. Wydział Technologii Materiałowych i Wzornictwa Tekstyliówpl_PL
dc.publisherLodz University of Technology. Press - Faculty of Material Technologies and Textile Designen_EN
dc.relation.ispartofseriesAutex Research Journal, Vol. 14, Issue 2, 2014en_EN
dc.subjectelectrospinningen_EN
dc.subjectresorbable materialen_EN
dc.subjectimplanten_EN
dc.subjectosseous tissue regenerationen_EN
dc.subjecthydroxyapatiteen_EN
dc.titleFabrication of Plga/Hap and Plga/Phb/Hap Fibrous Nanocomposite Materials for Osseous Tissue Regenerationen_EN
dc.typeArticleen_EN
dc.typeArtykułpl_PL

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