Browsing Artykuły (WCh) by Author "Małkiewicz, Andrzej"

Now showing items 1-2 of 2

Chemical synthesis of the 5-taurinomethyl(-2-thio)uridine modified anticodon arm of the human mitochondrial tRNALeu(UUR) and tRNALys

Leszczyńska, Grażyna; Leonczak, Piotr; Woźniak, Karolina; Małkiewicz, Andrzej (Cold Spring Harbor Laboratory Press, 2014)

5-Taurinomethyluridine (τm5U) and 5-taurinomethyl-2-thiouridine (τm5s2U) are located at the wobble position of human mitochondrial (hmt) tRNALeu(UUR) and tRNALys, respectively. Both hypermodified units restrict decoding ...
Site-selected incorporation of 5-carboxymethylaminomethyl(- 2-thio)uridine into RNA sequences by phosphoramidite chemistry

Leszczyńska, Grażyna; Pięta, Jakub; Woźniak, Karolina; Małkiewicz, Andrzej (2014)

5-Carboxymethylaminomethyluridine (cmnm5U) and 5-carboxymethylaminomethyl-2-thiouridine (cmnm5s2U) are located at the wobble position in several cytosolic and mitochondrial tRNA sequences. In this paper, we report the first ...