Witamy w Repozytorium PŁ

Repozytorium Politechniki Łódzkiej gromadzi, archiwizuje oraz udostępnia w postaci pełnotekstowej dorobek naukowy pracowników PŁ.

Repozytorium zawiera przede wszystkim artykuły naukowe, książki, monografie, materiały konferencyjne oraz referaty, powstałe jako wynik procesów badawczych i dydaktycznych prowadzonych przez Politechnikę Łódzką.

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Najnowsze publikacje

  • Item type:Pozycja,
    Profesor dr hab. inż. Janusz Marian Rosiak (1946 – 2024) wybitny uczony, wynalazca i dydaktyk
    (Faculty of Chemistry, Lodz University of Technology) Ulański, Piotr
  • Item type:Pozycja,
    Eliksir : czasopismo naukowo-dydaktyczne Wydziału Chemicznego Politechniki Łódzkiej nr 13/2024
    (Wydział Chemiczny, Politechnika Łódzka, 2024) Czylkowska, Agnieszka [Red. naczelny]
  • Item type:Pozycja,
    Polityki wspólnotowe w wieloszczeblowym zarządzaniu w Unii Europejskiej – wybrane przykłady
    (Wydawnictwo Politechniki Łódzkiej, 2025) Greta, Marianna; Dworak, Edyta (Rec.); Lewandowski, Krzysztof (Rec.)
  • Item type:Pozycja,
    Polyol sweeteners and platelet activation: implications for cardiovascular risk
    (Lodz University of Technology Press) Szustak, Marcin
    Erythritol and xylitol, long considered safe and metabolically inert sugar substitutes, are now drawing scientific attention for reasons beyond glycemic control. Recent findings suggest that these polyols may influence platelet function and thrombosis risk. In vitro and in vivo studies have shown that both compounds can enhance platelet responsiveness to classic agonists such as ADP and thrombin. These effects affect changes in intracellular calcium dynamics, integrin activation and granule secretion. What is most important, these responses occur at physiologically relevant concentrations. However, interpretation is complicated by the fact that erythritol and xylitol are not only diet-derived; both can be synthesized endogenously via the pentose phosphate pathway. As a result, elevated plasma levels may reflect an adaptive response or pathological state rather than direct intake alone. Mechanistically, the pathways involved remain poorly defined but early data suggest potential overlap with signaling cascades modulated by statins – including those dependent on isoprenoid intermediates. These findings open a new field for investigation into whether polyols act as modifiers of platelet activation or as biomarkers of metabolic imbalance. To turn things more complicated, the gut microbiota, chronic polyol exposure and individual cardiovascular risk profiles add further complexity to this relationship. A clearer understanding will require integrated studies that bridge biochemistry, clinical data and nutrition science. In this review, I critically assess the emerging evidence on erythritol and xylitol in the context of platelet biology and thrombotic risk. I also explore how these polyols might intersect with known metabolic and signaling pathways, to clarify whether their effects are harmful, adaptive, or context-dependent.
  • Item type:Pozycja,
    Sugar beet and beet pulp – a sustainable source of bioactive compounds
    (Lodz University of Technology Press) Kołodziejczyk, Krzysztof; Molska, Magdalena; Gruska, Radosław Michał
    Sugar beet (Beta vulgaris L.), traditionally cultivated for sugar production, has emerged as a promising source of diverse bioactive compounds with significant health-promoting potential. This review explores the phytochemical profile and biological activities of key constituents found in sugar beet and its by-products, including saponins, betaine, polysaccharides, and polyphenols. These compounds are increasingly valued for their antioxidant, anti-inflammatory, anticancer, antimicrobial and hepatoprotective properties, supporting their integration into functional foods, nutraceuticals and pharmaceuticals. Triterpenoid saponins in sugar beet roots, leaves and pulp demonstrate broad pharmacological activity, notably in immune modulation and cancer suppression. Betaine, highly concentrated in beet molasses and leaves, serves critical roles in methylation processes, osmoregulation and liver protection, while also contributing to cardiovascular health by reducing homocysteine levels. Polysaccharides, particularly from sugar beet pulp, exhibit valuable structural and functional properties for bioplastic development and dietary fiber enrichment, with emerging applications in green biorefineries. Additionally, polyphenols, especially flavonoids and phenolic acids, present strong antioxidant and vascular protective effects, with their extraction increasingly facilitated by eco-friendly technologies. Beyond their health benefits, the valorization of sugar beet by-products aligns with sustainability goals by promoting circular bioeconomy strategies. As research advances in optimizing extraction methods and understanding bioavailability, sugar beet is positioned to become a sustainable and industrially scalable source of high-value bioactive compounds. This underscores its relevance not only in agriculture but also in health and environmental innovation.